STUDI AKTIVITAS ANTIMIKROB HIDROGEL KITOSAN-PVP-ALGINAT SEMI-IPN (INTERPENETRATING POLYMER NETWORK)

Autor(s): Kartini Afriani, Tri Sutanti Budikania
DOI: 10.55075/wa.v43i1.168

Sari

 Hidrogel kitosan-poli-vinilpirolidon-alginat (CS/PVP/Alg) telah dapat disintesis dengan menggunakan Ca2+, Zn2+ dan formaldehida sebagai agen pengikat silang (crosslinker). Hidrogel yang terbentuk diuji aktivitasnya sebagai antimikrob yaitu sebagai antibakteri dan anti jamur dengan metode difusi agar. Hidrogel CS/PVP/Alg memiliki aktivitas antimikrob terhadap bakteri Bacillus subtilis dan jamur Aspergillus plapus. Untuk hidrogel dengan pengikat silang Ca2+ juga memberikan aktivitas antimikrob terhadap Escherichia coli sedangkan hidrogel dengan pengikat silang formaldehid hanya memberikat aktivitas antijamur terhadap Aspergillus plapus.

 

Kata Kunci: kitosan, poli vinilpirolidon, alginat, aktivitas antimikrob.

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Referensi

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DOI: https://doi.org/10.55075/wa.v43i1.168

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